Lignin-Based Nanocarrier for Simultaneous Delivery of ¹³¹I and SN-38 in the Combined Treatment of Solid Tumors by a Nanobrachytherapy Approach.

The statistical analysis of the antitumor effect by two-way ANOVA shows that, while the control and lignin-treated groups are not statistically different, proving that lignin itself does not cause any significant antitumor effect, there is highly significant statistical difference ( p << 0.01) of the averages of calculated volumes of all the three treated tumor groups ( Figure 4 A) as well as the final masses of the excised tumors at day 14 ( Figure 4 E).

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