Intestinal Probiotic Lysate Modified Bifunctional Nanoparticle for Efficient Colon Cancer Immunotherapy.

Pharmaceutics · 2025 · PMC11859493 · PMID 40006507

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a decreasing trendno p-value reported

Additionally, as shown in Figure 7 E, the weight of the tumors and the number of tumor nodes showed a decreasing trend, revealing the synergistic effect of DMPLAC and CD47-gene silencing in inhibiting tumor development.

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an increasing trendno p-value reported

Moreover, compared with the control group, the CD8+/CD4+ ratios in the DMP, LAC, and DMPLAC groups showed an increasing trend.

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