Urinary 4-pyridoxic acid as a non-invasive biomarker for evaluating osteoarthritis severity: findings from the ROAD study.

Aging Clin Exp Res · 2025 · PMC11861211 · PMID 40000531

Europe PMC DOI

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0.0650

closest p · 1.3× alpha

0.0650

boldest claim

The sentences

a weak trendp = 0.065so close (0.05 < p ≤ 0.1)

Contrastingly, a comparison of the 4PA values between each pair of KL grades for the lumbar spine showed no significant differences, although a weak trend was observed, with KL grade 4 tending to be higher than KL grades 1, 2, and 3 (KL grade 4 vs KL grade 1, p = 0.065; KL grade 4 vs KL grade 2, p = 0.090; KL grade 4 vs KL grade 3, p = 0.091).

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