Accrual of Alzheimer's disease pathology as a function of proximity to parental dementia onset.

Alzheimers Dement (Amst) · 2025 · PMC11865705 · PMID 40018326

Europe PMC DOI

hedged sentences

0.0820

closest p · 1.6× alpha

0.0820

boldest claim

The sentences

a trend toward significancep = 0.082so close (0.05 < p ≤ 0.1)

However, a trend toward significance was noted for the Favourites test subscore ( p = 0.082) and education level interacted significantly with PPO to predict performance on this test ( p = 0.030).

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of borderline significanceno p-value reported

However, it was noted that the graphically apparent protective effect of APOE‐ ε 2 was of borderline significance and the number of subjects carrying 2/4 ( n = 25) and 4/4 ( n = 30) combinations was small relative the number carrying 3/4 ( n = 225).

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