The effect of intraoperative low-dose ketamine versus dexmedetomidine infusion on postoperative bowel recovery in patients undergoing gastrointestinal malignancy surgeries: Placebo-controlled, randomized trial.

J Anaesthesiol Clin Pharmacol · 2025 · PMC11867358 · PMID 40026739

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could be considered significantno p-value reported

Previous studies have shown that a 1-day difference in time to passage of flatus could be considered significant.[ 9 , 10 ] Accordingly, allowing for a standard deviation (SD) of 1 day, a total sample size of 84 was calculated (28 in each group) to detect a difference of at least 1 day in the time to passage of flatus and/or stool.

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