The results showed that the mRNA and protein expression of GRP78 and C/EBP homologous protein (CHOP) were increased or showed an increasing trend in the PDE females (Figure 2J–N ), while there were no significant changes in GRP78 and CHOP expression in the PDE males (Figure 2J–N ).
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Cholesterol-27α-hydroxylase inhibitor nilvadipine can effectively treat cholestatic liver injury in adult offspring induced by prenatal dexamethasone exposure.
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