An increasing trend in antibacterial activity was found as the spacer length ( n ) increased from 2 to 3, further to 4, and ultimately to 6.
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Development of xanthone derivatives as effective broad-spectrum antimicrobials: Disrupting cell wall and inhibiting DNA synthesis.
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The sentences
Conversely, a decreasing trend in antibacterial activity was noted as the spacer length increased from 6 to 8 and further to 12.