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Development of xanthone derivatives as effective broad-spectrum antimicrobials: Disrupting cell wall and inhibiting DNA synthesis.

Sci Adv · 2025 · PMC11881906 · PMID 40043104

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an increasing trendno p-value reported
An increasing trend in antibacterial activity was found as the spacer length ( n ) increased from 2 to 3, further to 4, and ultimately to 6.

also in 63,971 other papers

a decreasing trendno p-value reported
Conversely, a decreasing trend in antibacterial activity was noted as the spacer length increased from 6 to 8 and further to 12.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.