Long-term health-related quality of life in Kawasaki disease complicated with coronary artery aneurysm in the Nanjing region of China: Results of the largest single-center assessment.

mc yes pmc-license-ref CC BY-NC Introduction Kawasaki disease (KD) is an acute self-limited vasculitis with an intense inflammatory process accounting for the most common cause of acquired heart disease in children mostly below five years of age.[ 1 ] The epidemiological surveys from China reported an increasing trend in the incidence of KD, and data from Beijing and Shanghai were documented to be about 46.3 to 55.1 per 100,000 in cases aged <5 years during the past decades.[ 2 ] The diagnosis of KD is challenging given the variety of clinical symptoms based on the presence of fever and a cluster of mucocutaneous manifestations, which usually creates difficulties and delays clinical treatment.[ 3 ] During the acute phase, there is a predilection for cardiovascular complications such as valvulitis, myocarditis, pericarditis, and KD syndrome.

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