When animals were maintained on standard diet, there was a nonsignificant trend for slightly higher plasma aldosterone values in Tmprss2 −/− mice compared with Tmprss2 +/+ mice (Figure 5 C), averaging 187±24 and 138±19 pg/ml, respectively.
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Transmembrane Serine Protease 2 and Proteolytic Activation of the Epithelial Sodium Channel in Mouse Kidney.
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