Southeast Asia burden and trend of Gastrointestinal tract cancers from 1990 to 2021 and its prediction to 2050: findings from the Global Burden of Disease Study 2021.

Furthermore, there is an increasing trend toward earlier onset of GI cancers, particularly CRC, PC, and GBTC, among younger populations [ 4 ].

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LC experienced a decreasing trend in the 65–74 age group, with an increase in the 80 + age group (Fig. 4 D).

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