The Compensatory Effect of S375F on S371F Is Vital for Maintaining the Infectivity of SARS-CoV-2 Omicron Variants.

J Med Virol · 2025 · PMC11891949 · PMID 40062404

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highly significantno p-value reported

Compared with the D614G RBD, the RBD with the S371F mutation presented a highly significant conformational change in the α1 and α2 secondary structures, followed by S371F + S375F.

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