extremely significantP < 0.01
The results showed that PPPm-1 had good anti-fatigue effects, which could significantly prolong the weight-bearing swimming time of mice ( P < 0.01), reduce the levels of blood lactate and serum urea nitrogen in mice after exercise fatigue, and increase the levels of liver glycogen and muscle glycogen in mice (most differences are extremely significant P < 0.01) ( Hao and Sha, 2024 ). 5 mg/mL PPPm-1 could significantly promote the contraction amplitude, contraction rate, and relaxation rate of frog gastrocnemius muscle, as well as the ACh content at the junction of frog sciatic nerve and gastrocnemius muscle ( P < 0.01), but had a significant inhibitory effect on the AChE activity at the junction of frog sciatic nerve and gastrocnemius muscle ( P < 0.01) ( Hao and Sha, 2024 ).