Proteo-metabolomic insights for early dual physical and cognitive impairments: A search for biomarkers of healthy aging based on muscle-brain crosstalk.

Aging Cell · 2025 · PMC11896308 · PMID 39517120

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

a decreasing trendno p-value reported

Disrupted glutathione and amino acid metabolism in PCDS In the glutathione pathway, the PCDS group showed a significant increase of aminopeptidase N (ANPEP) and glutathione S‐transferase pi (GSTP1), accompanied by a decreasing trend of pyroglutamic acid (5‐oxoproline) (Figure 4a ), indicating the dysregulation of glutathione homoeostasis.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.