High prevalence of carbapenem-resistant <i>Pseudomonas aeruginosa</i> and identification of a novel VIM-type metallo-β-lactamase, VIM-92, in clinical isolates from northern China.

During the 3-year period, the resistance rate to piperacillin-tazobactam initially declined but then increased ( p < 0.05), while resistance to ceftazidime-avibactam, aztreonam, imipenem, ciprofloxacin, levofloxacin, and amikacin showed a decreasing trend ( p < 0.05).

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