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7 Tesla MRI Reveals Brain Structural Abnormalities and Neural Plasticity in RPGR-Related Retinitis Pigmentosa.

J Clin Med · 2025 · PMC11900292 · PMID 40095571

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Results: The mean LGN volume (right—100 mm 3 , left—96 mm 3 ) and left lingual gyrus volume (6162 mm 3 ) were significantly lower in RPGR patients in comparison to the control group (129 mm 3 , 125 mm 3 , and 7310 mm 3 , respectively), whilst some brain regions related to other sensory information such as the left isthmus cingulate (3690 mm 3 ) and entorhinal cortex (right—1564 mm 3 , left 1734 mm 3 ) were significantly or almost significantly higher in the RPGR group than in the control group (2682 mm 3 , 960 mm 3 , and 1030 mm 3 , respectively).

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