highly significantp < 0.001
All statistical tests were 2-sided, and p < 0.05 (*) were considered statistically significant, p < 0.01 (**) highly significant, and p < 0.001 (***) extremely significant. 5.
All statistical tests were 2-sided, and p < 0.05 (*) were considered statistically significant, p < 0.01 (**) highly significant, and p < 0.001 (***) extremely significant. 5.