CD38 mediates nicotinamide mononucleotide base exchange to yield nicotinic acid mononucleotide.

J Biol Chem · 2025 · PMC11903787 · PMID 39894219

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a slight trendno p-value reported

There was a slight trend toward increased nicotinic acid with CD38 treatment, however as described above, this was not correlated with decreased NaMN levels, suggesting that there is minimal NaMN cleavage by CD38.

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