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Global, regional, and national epidemiology of ischemic heart disease among individuals aged 55 and above from 1990 to 2021: a cross-sectional study.

BMC Public Health · 2025 · PMC11905664 · PMID 40075403

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an increasing trendno p-value reported
Conversely, a positive value for both EAPC and its lower limit of the 95% CI implies an increasing trend in that rate.

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a decreasing trendno p-value reported
Results The global incidence rate, mortality rate, and DALYs rate for individuals aged 55 and above with IHD have shown a decreasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.