Evaluation of toxicity, local biocompatibility, biodegradation, and systemic metabolism of cellulose/alginate/strontium apatite membranes implanted subcutaneously in mice.

Lymphocyte concentrations vary according to membrane composition, with a decreasing trend: high to low from one to 12 weeks with PLGA and PTMC 26 , moderate to low one to nine weeks with collagen-apatite 23 , low up to three weeks and zero in nine weeks with collagen-apatite-nanokeratin 22 or moderate from one to three weeks and low in nine weeks with alginate-capsul 27 .

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