Short-term oral zinc supplementation enhances Natural Killer cell functionality and decreases circulating Innate Lymphoid Cell counts and frequencies in healthy young adults.

J Transl Med · 2025 · PMC11909903 · PMID 40087783

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a decreasing trendno p-value reported

Although the cILC2 CD117 +/− subsets also showed a decreasing trend, this change was not statistically significant.

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almost significantno p-value reported

As we observed an almost significant trend in CD69 + cILCs between ZA and ZD study participants (Fig. 2 E), we also evaluated CD69 expression on cILCs before and after zinc supplementation.

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a near significant trendno p-value reported

Prior to zinc supplementation, individuals classified as ZD in serum zinc showed a near significant trend towards reduced CD69 expression on total cILCs as well as on cILC1 and cILC3.

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