First, there may not be significant differences in its gene expression levels because MAPK14’s functional role in sepsis development is mainly dependent on its phosphorylation. 39 Second, our in vitro validation model was the septic lung injury model and other sepsis injury models may exhibit differential MAPK14 expression at the gene level.
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From Gene to Intervention: NLRC4 and WIPI1 Regulate Septic Acute Lung Injury Through Autophagy.
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