Interferon Regulatory Factor 3 Exacerbates the Severity of COVID-19 in Mice.

Crit Care Explor · 2025 · PMC11918655 · PMID 40103621

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a slight trendno p-value reported

We observed a slight trend toward attenuated weight loss in IRF3 knockout vs. wild-type mice ( Fig. 1 C ).

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borderline significanceno p-value reported

wild-type mice at day 2 post-infection and also found lower levels (borderline significance) at day 4 post-infection ( Fig. 2 B ).

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