Population genomic analysis identifies the complex structural variation at the fibromelanosis (FM) locus in chicken.

Sci Rep · 2025 · PMC11920206 · PMID 40102581

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The fact that EDN3 shows a highly significant upregulation at the mRNA level in skin from FM chickens strongly suggested that this is the causal mechanism for the massive expansion of pigment cells in FM chicken 2 .

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