Barely Significant
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Pharmacokinetics and Safety Profile of SNS812, a First in Human Fully Modified siRNA Targeting Wide-Spectrum SARS-CoV-2, in Healthy Subjects.

Clin Transl Sci · 2025 · PMC11926758 · PMID 40116355

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a decreasing trendno p-value reported
Although a decreasing trend in neutrophil count was observed from baseline compared to placebo 4 days post‐dosing at the highest dose of SNS812 in the MAD cohort, there was no significant difference between groups (Figure S1 ).

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