After stimulating the cells with LPS (lipopolysaccharide) for 2 h, we observed an increasing trend in the expression of Hnrnp c and upregulation of various cytokines including Tnf-α , Il1β , Il18 , Inos , and Il6 ( Figure 3 A).
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The m6A reader HNRNPC is a key regulator in DSS-induced colitis by modulating macrophage phenotype.
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