Barely Significant
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Synergistic effects of memantine and alpha7 nicotinic acetylcholine receptor agonist PHA-543613 to improve memory of aged rats.

Int J Neuropsychopharmacol · 2025 · PMC11929953 · PMID 39985181

Europe PMCDOI
1
hedged sentence
0.0810
closest p · 1.6× alpha
0.0810
boldest claim

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marginally significantP = .081so close (0.05 < p ≤ 0.1)
Effects of Aging on Brain Expression Levels of Selected Marker Proteins Results of ELISA analysis revealed a marginally significant increase of proinflammatory IL-1β protein level in the STR of AU but not of AI animals compared to the young control group ( n = 5/group; F(2, 12) = 3.127, P = .081; AU vs young: 1.5 ± 0.1 pg/μg vs 1.1 ± 0.1 pg/μg, P = .032; AI vs young: 1.4 ± 0.1 pg/μg vs 1.1 ± 0.1 pg/μg, P = .110) ( Figure 5B ).

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