Barely Significant
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The burden of refraction disorders in 204 countries and territories from 1990 to 2021: A systematic analysis from the global burden of disease 2021.

Adv Ophthalmol Pract Res · 2025 · PMC11930593 · PMID 40134666

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a decreasing trendno p-value reported
In most regions with lower SDI, the AAPCs are greater than 0, indicating an increasing burden, while in other regions, the AAPCs are generally below 0, indicating a decreasing trend ( Fig. 2 C and D). 3.3.

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an increasing trendno p-value reported
They showed an increasing trend between 1995 and 2001 (APC ​= ​0.15) and between 2015 and 2019 (APC ​= ​0.26), followed by a rapid decline between 2019 and 2021 (APC ​= ​−0.72).

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