Oral antimicrobial prophylaxis was associated with preventing surgical site infection following 2-stage restorative proctocolectomy in patients with ulcerative colitis.

Although there were differences across years, the linear regression revealed a decreasing trend in the SSIs.

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Conversely, there was an increasing trend in the rate of biologic administration, and the regression equation was y = 0.9906x + 31.389: R 2 = 0.2168.

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