A TBX2-driven signaling switch from androgen receptor to glucocorticoid receptor confers therapeutic resistance in prostate cancer.

Oncogene · 2025 · PMC11932930 · PMID 39702503

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highly significantno p-value reported

Spearman correlation analysis of TF activity levels revealed consistent and highly significant correlations in both cohorts: 1) a negative correlation between TBX2 and AR (Fig. 7A, D ), 2) a positive correlation between TBX2 and GR (Fig. 7B, E ), and 3) a negative correlation between AR and GR (Fig. 7C, F ).

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