highly significantP < 3.258 × 10 −21
The mean ΔPPD ( ± SE) for the bTB+ animal group was 1170.35 ± 84.48 compared to −360.46 ± 55.17 for the bTB− group and this group difference was highly significant (two-tailed Wilcoxon rank-sum test; P < 3.258 × 10 −21 ) (Supplementary Fig.