Epidemiological characteristics of 5838 cases of enterovirus infection in children in Hangzhou from 2018 to 2023.

Sci Rep · 2025 · PMC11933370 · PMID 40128330

Europe PMC DOI

hedged sentences

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closest p · 0.2× alpha

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an increasing trendP < 0.01actually significant

Although the number of samples decreased compared with 2018 and 2019, the positive detection rate of EV nucleic acid still showed an increasing trend, showing a statistically significant difference between the positive detection rates of EV nucleic acid across different years (χ 2 = 441.62, P < 0.01), as shown in Table 1 .

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a decreasing trendno p-value reported

The monovalent EV-A71 vaccine was approved in China in 2016, following which the number of severe cases and deaths of HFMD caused by EV-A71 showed a decreasing trend.

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