Barely Significant
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Global, regional, and national burden of infective endocarditis from 2010 to 2021 and predictions for the next five years: results from the Global Burden of Disease Study 2021.

BMC Public Health · 2025 · PMC11934598 · PMID 40128765

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an overall trendno p-value reported
At the regional level, significant variations in the ASPR were observed, with an overall trend of increasing rates that correlates positively with the SDI.

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