Unraveling the molecular mechanisms of Fufangduzhong formula in alleviating high-fat diet-induced non-alcoholic fatty liver disease in mice.

Additionally, HFD remarkedly triggered the inflammatory responses, leading to increases in serum IL-6 and TNF-α levels in the HFD-induced mice by 88.24% and 69.05%, respectively, compared with the ND group, whereas those levels exhibited a decreasing trend as the FFDZ dose increased ( Figures 3J, K ).

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Following treatment with FFDZ, serum SOD and GPx levels exhibited an increasing trend with higher doses of the drug, particularly in the high-dose FFDZ group, where the levels were comparable to those in the NC group.

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