The MicroRNA miR-454 and the mediator complex component MED12 are regulators of the androgen receptor pathway in prostate cancer.

Sci Rep · 2025 · PMC11937531 · PMID 40133664

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partially significantno p-value reported

The knockdown of MED12 had the most effective and significant effect on reducing MED12, AR, AR-V7 and c-Myc protein expression in the DuCaP EnzR cell line and had a lesser and only partially significant effect on MED12, AR and c-Myc expression in the LNCaP Abl EnzR cell line.

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