Anti-ADAMTS13 Autoantibodies in Immune-Mediated Thrombotic Thrombocytopenic Purpura.

Antibodies (Basel) · 2025 · PMC11939265 · PMID 40136473

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Anti-ADAMTS13 autoantibodies are polyclonal in nature, and they have been found targeting all ADAMTS13 domains at one point or another; nevertheless, the central cysteine-rich spacer region appears to be the set of epitopes that is highly significant in the development of iTTP.

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