E-Cadherin Is Important in the In Vitro Postnatal Development and Function of Pig Islets.

For SNAP25 protein expression, a decreasing trend was apparent across all ages of pigs ( Figure 4 D–F, Table S11 ).

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Results : Despite no significant difference observed in gross morphology and viability, as well as variable expression of RAC1, insulin, and SNAP25 in islets from 1-, 3-, and 7-day-old neonatal pigs, there was an apparent trend towards improved function in islets obtained from 3- and 7-day-old pigs compared with 1-day-old pigs.

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While a variable trend was observed in islets from 3-day-old pigs, with an increasing trend in gene expression seen on Day 5 of culture ( Figure 3 D).

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