highly significantp -value < 0.01
All the statistical analyses were performed via nonpaired two-tailed t -tests (a p -value < 0.05 was considered significant, and a p -value < 0.01 was considered highly significant).
All the statistical analyses were performed via nonpaired two-tailed t -tests (a p -value < 0.05 was considered significant, and a p -value < 0.01 was considered highly significant).