Integrative Analysis of ATAC-Seq and RNA-Seq Identifies Key Genes Affecting Muscle Development in Ningxiang Pigs.

HOXA10 exhibits highly significant differential expression and differential chromatin openness across multiple stages, and in conjunction with existing literature reports, we speculate that HOXA10 may be key candidate genes regulating the growth and development of pig skeletal muscle.

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The density of muscle fibers showed a decreasing trend with age, with average daily decreases of 58.21, 20.70, 7.19, and 2.75 fibers/mm 2 ( Figure 1 E).

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These findings suggest that the HOXA10 genes may be significant target genes for pig skeletal muscle development in our study.

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