Evaluation of the Antinociceptive Effect of Sesamin: Role of 5HT<sub>1A</sub> Serotonergic Receptors.

In the dose–response curves, it is shown that sesamin significantly and dose-dependently reduced formalin-induced nociception between 0.32 and 3.2 mg/kg along phase 2, but only showed a decreasing trend during phase 1.

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