Parenteral Nanoemulsion for Optimized Delivery of GL-II-73 to the Brain-Comparative In Vitro Blood-Brain Barrier and In Vivo Neuropharmacokinetic Evaluation.

In contrast, the AUC 0–36 values for GL-II-73 from the nanoemulsion tended to be higher compared to the solution, although the difference was of borderline significance ( p = 0.050), which is likely due to inter-individual variation.

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It is important to note that borderline significant results (e.g., p values close to 0.05) should be interpreted with caution.

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p values less than 0.05 were considered statistically significant, with p < 0.01 and p < 0.001 indicating highly significant and very highly significant results, respectively.

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