Barely Significant
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CRISPR targeting of SNPs associated with age-related macular degeneration in ARPE-19 cells: a potential model for manipulating the complement system.

Gene Ther · 2025 · PMC11946884 · PMID 40102632

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highly significantno p-value reported
In 2005, a genome-wide association study (GWAS) identified a highly significant genetic variant in CFH (Tyr402His) [ 4 ], a finding corroborated by other studies [ 5 , 22 , 23 ].

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