623 Here, we discuss recent developments of nanosensors to monitor neurotransmitter release with high spatial resolution to monitor neurochemical activity in the brain with nanotechnologies. Highly significant advances have been achieved in the detection of catecholamines, dopamine and norepinephrine, using NIR nanosensors based on functionalized single-walled carbon nanotubes (SWCNTs) 624 − 627 and acetylcholine, using DNA-based enzymatic nanosensors. 628 Carbon nanotubes are formed by multiple parallel concentric graphene cylinders. 629 Single-walled carbon nanotubes (SWCNTs) are CNTs formed by a single graphene cylinder with interesting properties that depend on the surrounding environment (reviewed in O’Connell et al . 630 ).
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