Intestinal overexpression of <i>Pla2g10</i> alters the composition, diversity and function of gut microbiota in mice.

The abundance of Actinobacteria in the colonic chyme of the Pla2g10 KI group had an upward trend compared with the control group, whereas the abundance of Bacteroidetes was significantly lower ( Figure 5A ), and the Firmicutes/Bacteroidetes (F/B) ratio also showed an increasing trend in the Pla2g10 KI mice ( Supplementary Figure 1B ).

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