Efficacy and Safety of Andexanet Alfa Versus Four Factor Prothrombin Complex Concentrate for Emergent Reversal of Factor Xa Inhibitor Associated Intracranial Hemorrhage: A Systematic Review and Meta-Analysis.

Neurocrit Care · 2025 · PMC11950062 · PMID 39379749

Europe PMC DOI

hedged sentence

0.0460

closest p · 0.9× alpha

0.0460

boldest claim

The sentences

marginally significantP = 0.046actually significant

Twelve studies including 1,178 patients assessed the incidence of thromboembolic events, and more events were found in the AA group; however, the results were marginally significant (RR 1.47, 95% CI 1.01–2.15, P = 0.046).

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