an increasing trendp = 0.001
Regarding SD clusters, we found an increasing trend in ORx and OSRx average within 60 min just before SD clusters, as seen in the positive slopes derived from the fitted linear mixed-effects model (0.0013 [ p = 0.001] for ORx and 0.0009 [ p = 0.0001] for OSRx, respectively; Table 2 ) We also found a decreasing trend in ORx within 60 min just after SD clusters (− 0.0008, p = 0.0288) but no significant trend in OSRx post-SD clusters.