In Vox-treated tumors, Ifn-b was upregulated in neutrophils and macrophages and Ifn-g (almost significant), Isg15 and Grzb in total immune cells.
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Oxaliplatin, ATR inhibitor and anti-PD-1 antibody combination therapy controls colon carcinoma growth, induces local and systemic changes in the immune compartment, and protects against tumor rechallenge in mice.
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