Global, Regional, and National Burden of Non-Rheumatic Valvular Heart Diseases in Women: A Systematic Analysis of Global Burden of Disease 1990-2021.

Glob Heart · 2025 · PMC11951974 · PMID 40161863

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an increasing trendno p-value reported

Background: The incidence of non-rheumatic valvular heart diseases (NRVHD) has shown an increasing trend.

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a decreasing trendno p-value reported

On a global scale, YLDs and prevalence related to heart failure due to NRVHD have shown a decreasing trend from 1990 to 2021 (3.56 vs 2.63 in YLDs, 39.74 vs 29.45 in prevalence).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.