Barely Significant
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Blocking mineralocorticoid signaling with esaxerenone reduces atherosclerosis in hyperglycemic ApoE KO mice without affecting blood pressure and glycolipid metabolism.

Sci Rep · 2025 · PMC11954868 · PMID 40157997

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a decreasing trendno p-value reported
Second, although there was no significant difference in expression levels of mRNA, inflammatory cytokines showed a decreasing trend.

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