Development and evaluation of RhizoQOL, a quality-of-life caregiver-reported survey for rhizomelic chondrodysplasia punctata, a rare peroxisomal disorder.

Orphanet J Rare Dis · 2025 · PMC11956500 · PMID 40165314

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

an overall trendno p-value reported

In addition, while a statistically significant change may not be feasible, an overall trend of improvement on the RhizoQOL would provide strong support for the clinical meaningfulness of changes observed in primary or secondary endpoints.

also in 4,871 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.