While differences in rwOS among BRAF mutation classes were not statistically significant, a numerical trend towards superior rwOS was noted among those with class III mutations, which is consistent with previously observed positive prognostic value of class III mutations in colorectal cancer; notably low numbers of patients with this type of mutation in CCA does limit analysis to some extent. 28 Outcomes
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Frequency and outcomes of BRAF alterations identified by liquid biopsy in metastatic, non-colorectal gastrointestinal cancers.
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